Deinococcus N-acylamino acid racemase and use of preparing...

Details Deinococcus N-acylamino acid racemase and use of preparing... Deinococcus N-acylamino acid racemase and use of preparing...

2005-12-27

2009-12-08

Steadman, David J (Department: 1656)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

C435S091100, C536S025300

Reexamination Certificate

active

07629154

ABSTRACT:
The present invention relates to a novel thermostable N-acylamino acid racemase (NAAAR) isolated fromDeinococcus radioduransNCHU1003, the coding sequence and the preparation thereof. The present invention also discloses the process for preparing highly optically pure L-amino acids, such as L-homophenylalanine (L-HPA) and the derivatives thereof, from N-protected amino acid by using the novel NAAAR combined with L-N-carbamoylase.

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