Dehydrodidemnin B as an L-type calcium channel enhancer

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Patent

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Details

514 11, 530317, A61K 3800, C07K 500, C07K 700, C07K 1600

Patent

active

060309431

ABSTRACT:
This invention relates to a new use discovered for the compound known as Aplidine (dehydrodidemnin B) which has the following structure: Aplidine has been found to be a potent L-type calcium channel enhancer in the human heart. This effect makes Aplidine a very useful drug for the treatment of congestive heart failure, as well as useful for the treatment of atrial fibrillation.

REFERENCES:
patent: 5580871 (1996-12-01), Earl

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