Dehydrodidemnin B

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Peptides containing saccharide radicals – e.g. – bleomycins – etc.

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530317, 514 11, 514 9, 514 8, 514 2, 930270, 930DIG546, 930DIG549, C07K 1100, A61K 3815

Patent

active

058345868

ABSTRACT:
Dehydrodidemnin B with useful biological activity has formula (1). It can be isolated from natural sources or synthesized, and it forms active derivatives. ##STR1##

REFERENCES:
patent: 4493796 (1985-01-01), Rinehart, Jr.
patent: 5294608 (1994-03-01), Rinehart
K. L. Rinehart, Jr., J. Am. Chem. Soc. vol. 103, pp. 1857-1859 (1981).
Montgomery, D. W., Zukoski, C. F., Trasnplantation, vol. 40, pp. 49-56 (1985).
Montgomery et al., Fed. Prac., vol. 44, p. 634 (1987).
Rinehart, Jr. et al., Pure and Appl. Chem., vol. 54, pp. 2409-2424 (1982).
Rinehart, Escom , "Didemnin and its Biological Properties", pp. 626-631, (1987).
Rinehart et al, J. Am. Chem. Soc., vol. 109, pp. 6846-6848 (1987).

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