Dehydrating decomposition process for preparing carbonyl compoun

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

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568486, C07C 4552

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045543828

ABSTRACT:
Dehydrating decomposition of compound (I), i.e. gem-diol, hemi-acetal or hemi-ketal, by contact with sulfuric acid gives a carbonyl compound (II). ##STR1## Disclosed is a two-stage process in which the first stage is the contact of compound (I) with sulfuric acid at 90.degree.-140.degree. C. so as to partly decompose and dehydrate the compound (I), permitting the concentration of sulfuric acid to become lower than 93 wt. % but not lower than 65 wt. %, and the second stage is the contact of the product of the first-stage reaction with concentrated sulfuric acid at a temperature not higher than 60.degree. C., preventing the concentration of sulfuric acid from becoming lower than 93 wt %. For example, hexafluoroacetone is obtained from a hydrate thereof by this process using only a small amount of sulfuric acid.

REFERENCES:
patent: 2901514 (1959-08-01), Drysdale
patent: 3919328 (1975-11-01), Gutierrey et al.
patent: 3928459 (1975-12-01), Mercier
patent: 4304927 (1981-12-01), Krespan
Patai, The Chemistry of the Carbonyl Group, Interscience Publns, pp. 188-192, (1966).

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