Degradation and detection of TSE infectivity

Details Degradation and detection of TSE infectivity Degradation and detection of TSE infectivity

2007-12-04

2007-12-04

Naff, David M. (Department: 1651)

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Cleaning using a micro-organism or enzyme

C435S262000

Reexamination Certificate

active

10614370

ABSTRACT:
A transmissible spongiform encephalopathy (TSE) agent is inactivated by exposing the TSE agent to a thermostable proteolytic enzyme at elevated temperature and at acid or alkaline pH. Following this step, or separately, presence of TSE infectivity is detected by detection of dimers of prion protein.

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