Degradable heterobifunctional poly(ethylene glycol) acrylates

Details Degradable heterobifunctional poly(ethylene glycol) acrylates Degradable heterobifunctional poly(ethylene glycol) acrylates

2007-01-23

2007-01-23

Naff, David M. (Department: 1651)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

C435S174000, C435S181000, C436S518000, C436S532000, C525S054100, C530S402000, C530S810000, C530S816000

Reexamination Certificate

active

10684946

ABSTRACT:
A heterobifunctional poly(ethylene glycol) is provided having a hydrolytically degradable linkage, a first terminus comprising an acrylate group, and a second terminus comprising a target such as a protein or pharmaceutical agent or a reactive moiety capable of coupling to a target. Hydrogels can be prepared. The hydrogels can be used as a carrier for a protein or a pharmaceutical agent that can be readily released in a controlled fashion.

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