Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2010-02-23
2010-11-16
Noakes, Suzanne M. (Department: 1656)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C530S350000
Reexamination Certificate
active
07833981
ABSTRACT:
Deglycosylated long pentraxin PTX3 and desialidated long pentraxin PTX3 are disclosed, as well as processes for their preparation, pharmacological compositions containing them, and their use for the preparation of a medicament for the treatment of diseases in which the use of the long pentraxin PTX is indicated, particularly infectious and inflammatory diseases and female fertility disorders. These proteins are endowed with therapeutic activity superior to that of glycosylated pentraxin.
REFERENCES:
patent: 2004/0198655 (2004-10-01), Mantovani
patent: 2005/0043230 (2005-02-01), Presta et al.
patent: 2008/0026997 (2008-01-01), Carminati et al.
Bowie et al., “Deciphering the Message in Protein Sequences: Tolerance to Amino Acid Substitutions” Science, 1990, vol. 247, pp. 1306-1310.
Wells, J., “Additivity of Mutational Effects in Proteins” Biochemistry, 1990, vol. 29, No. 37, pp. 8509-8517.
Bottazzi, B. et al. “Multimer Formation and Ligand Recognition . . . ” The Journal of Biological Chemistry, vol. 272, No. 52, pp. 32817-32823, 1997.
Nauta, A. “Biochemical and Functional Characterization of the Interaction . . . ”, Eur. J. Immunol., vol. 33, pp. 465-473, 2003.
Hamazaki, H. “Structure and Significance of n-Linked Sugar Unit . . . ”, Biochemicica et Biophysica Acts., vol. 1037, pp. 435-438, 1990.
Siripont, J. et al. “Receptor-Mediated Binding of the Acute-Phase . . . ”, Cellular Immunology, vol. 117, pp. 239-252, 1988.
Tennent, G. et al. “Glycobiology of the Pentraxins”, Biochemical Society Transactions, vol. 22, No. 1, pp. 74-79, 1994.
Carminati Paolo
De Santis Rita
Inforzato Antonio
Salvatori Giovanni
Lucas & Mercanti LLP
Noakes Suzanne M.
Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
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