Deformylase

Details Deformylase Deformylase

1997-09-16

1999-10-05

Minnifield, Nita

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

4353201, 4351723, 4352523, 435 691, 536 232, 536 237, 536 2432, 536 254, C07H 2102, C07H 2104, C07H 2100, C12P 2100

Patent

active

059626666

ABSTRACT:
The invention provides def polypeptides and DNA (RNA) encoding def polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing def polypeptides to screen for antibacterial compounds.

REFERENCES:
patent: 5834243 (1998-11-01), Bogosian
patent: 5879905 (1999-03-01), Bhandary
Belouski et al, Current Microbiology, 36:248-249, 1998.
Meinnel et al, J. Bacteriology, 176(23):7387-7390 Dec. 1994.
Meinnel, et al.., GenBank Submission, Accession No.P43522, "Polypeptide deformylase (EC 3.5.1.3.1)(PDF) Formylmethionin."e.
Mazel, et. al., "Genetic characterization of Polypeptide deformylase, a distinctive enzyme of eubacterial translation." The EMBO Journal, vol. 13, No. 4, pp. 914-923, (1994).
Mazel, et. al., "A survey of polypeptide deformaylase function through the eubactrial lineage." JMB, (AP) Academy Press Limited, (1997) 266(5):939-949.

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