Defined surfaces of self-assembled monolayers and stem cells

Details Defined surfaces of self-assembled monolayers and stem cells Defined surfaces of self-assembled monolayers and stem cells

2006-08-15

2011-11-22

Bertoglio, Valarie (Department: 1632)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Solid support and method of culturing cells on said solid...

C435S402000, C435S283100, C435S366000, C435S375000

Reexamination Certificate

active

08062890

ABSTRACT:
A method for the construction of arrays from self-assembling monolayers is described. The arrays have particular utility for the screening of peptides ligands that can foster the growth of cells in culture. This technique has been used to identify peptide ligands that foster the growth of human stem cells, which otherwise require an extracellular matrix in order to grow in an undifferentiated state. This also makes possible an assay to identify other such peptides.

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