Defined medium OMPC fermentation process

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using a micro-organism to make a protein or polypeptide

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435101, 4352521, 4352536, C12N 120, C12P 2100

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active

054948088

ABSTRACT:
A new fermentation process for the culture of Neisseria meningitidis incorporates a wholly synthetic medium and event based processing decisions. This process is capable of generating cells at production scale for the extraction and purification of outer membrane protein complex (OMPC) vesicles which are useful as a protein carrier for PedvaxHIB.RTM. and pneumococcal conjugate vaccines.

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