Data processing: generic control systems or specific application – Specific application – apparatus or process – Nonreactive mixing process
Reexamination Certificate
2005-08-09
2005-08-09
Bahta, Kidest (Department: 2125)
Data processing: generic control systems or specific application
Specific application, apparatus or process
Nonreactive mixing process
C700S281000, C700S285000, C604S067000
Reexamination Certificate
active
06928338
ABSTRACT:
Decision information systems, methods, and computer programs for better informing decisions to use multiple drugs in drug delivery devices, including implantable devices, for drug administration. Executable computer programs and logic embodying methods of the invention can calculate consistent multiple drug mixture amounts and drug delivery flow rates. One program accepts user input indicating a desired first drug dose rate, an initial first drug concentration, a desired second drug dose rate, an initial second drug concentration, and the reservoir size of the drug delivery device. The program method calculates a first drug amount and a second drug amount to combine in a mixture as well as a first drug true concentration in the mixture. The drugs can be mixed consistent with the physician's instructions using the program output. The first drug true concentration can be entered into a programmer device as the only drug concentration entered. Another program calculates a consistent first drug, second drug, and diluent amount to be added to a mixture for injection into a fixed flow rate, implantable drug delivery device. Methods preferably output true concentrations and dose rates for all drugs to be added and most preferably show all calculations used to arrive at the flow rate and mixture amount calculations. Yet another program receives a new desired drug dose rate for a previously filled device. The program accepts the existing mixture volume and true drug concentrations for a partially depleted device and calculates a new mixture flow rate to achieve the desired dose rate using the existing mixture. The methods can be implemented as executable computer programs in programmer devices, general purpose computers, servers, handheld computers, and personal digital assistants.
REFERENCES:
patent: 5509404 (1996-04-01), Lloyd et al.
patent: 5772635 (1998-06-01), Dastur et al.
patent: 5915971 (1999-06-01), Ramsay et al.
patent: 6070102 (2000-05-01), Hartlaub et al.
patent: 6210361 (2001-04-01), Kamen et al.
patent: 6273727 (2001-08-01), Ramsay et al.
patent: 6740075 (2004-05-01), Lebel et al.
patent: 2005/0010166 (2005-01-01), Hickle
patent: 0319272 (1989-06-01), None
patent: WO96/36389 (1996-11-01), None
Altas, Glen, “Tutorial 25: Calculating Mixtures of Local Anesthetic and Morphine for Implantable Intrathecal Pumps”,Pain Digest(1996), vol. 6, pp. 232-236.
Buchser, E., et al., “Computer Assisted Calculation of Drug Mixture Composition for Intrathecal Drug Administration: A Presentation of the e-MICS Software”. This article was presented and distributed with the two page poster identified in (3) below at the “Worldwide Pain Conference 2000” conference in San Francisco on Jul. 15-17, 2000.
Buchser, E., et al., “e-MICS Drug Mixture Composition Software” (two-page poster). Presented and distributed at the “Worldwide Pain Conference 2000” in San Francisco on Jul. 15-17, 2000.
Buchser Eric E.
Crowley Thomas P.
Dummann Brian T.
Schultz Brenda K.
Valine Thomas J.
Bahta Kidest
Fredrikson & Byron , P.A.
Medtronic Inc.
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