Decay accelerating factor (DAF) and nucleic acids encoding it

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 697, 4351723, 435325, 4352523, 4353201, 536 235, 530350, 530829, 935 9, 935 10, C12N 1512

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057632243

ABSTRACT:
This application relates to nucleic acids encoding decay accelerating factor (hereinafter abbreviated as DAF), as well as vectors and cells which comprise such nucleic acids. Additionally, nucleic acids which encode variants of DAF, such as insertion, deletion or substitution variants, are described. This application also relates to the preparation of DAF in recombinant cell culture. In particular, it is concerned with the large scale manufacture of DAF suitable for pharmaceutical or diagnostic use.

REFERENCES:
patent: 3993754 (1976-11-01), Rahman
patent: 4480041 (1984-10-01), Myles et al.
patent: 4675285 (1987-06-01), Clark et al.
patent: 4687661 (1987-08-01), Kikuchi et al.
patent: 5109113 (1992-04-01), Caras et al.
patent: 5223394 (1993-06-01), Wallner
patent: 5264357 (1993-11-01), Caras et al.
patent: 5374548 (1994-12-01), Caras
ATCC-Cell Lines & Hybridomas 7:4 (1992) p. 4.
Bhown et al., "The Use of HPLC for in Protein Sequencing" Handbook For HPLC The Separation of Amino Acids, Peptides and Proteins 2:267-278 (1984).
Caras et al., "cDNA Cloning of Decay Accerlerating Factor Reveals Novel Use of Splicing to Generate Two Protein Forms" Molecular Genetics of Complement Workshop (MIT/Endicott House, Boston, MA. Oct. 18-20) (1986).
Dizdaroglu et al., "Comparision of Reversed-Phase and Weak Anion-Exchange High-Performance Liquid Chromatographic Methods for Peptide Separations" Journal of Chromatography 264:223-229 (1983).
Gahmberg et al., "Expression of the Major Sialoglycoprotein (Glycophorin) on Erythroid Cells in Human Bone Marrow" Blood 52(2):379-387 (1978).
Gubler and Hoffman, "A simple and very efficient method for generating cDNA librabies" Gene 25:263-269 (1983).
Hoffmann, E., "Inhibition of Complement by A Substance Isolated From Human Erythrocytes-I." Immunochemistry 6:391-403 (1969).
Hoffmann, E., "Inhibition of Complement By A Substance Isolated From Human Erythrocytes-II." Immunochemistry 6:405-419 (1969).
Hunkapiller et al., "Isolation of Microgram Quantities of Proteins From Polyacrylamide Gels for Amino Acid Sequence Analysis" Methods In Enzymology 91:227-236 (1983).
Johnstone et al., "Immunochemistry In Practice" Blackwell Scientific Publications pp. 210-211 (1982).
Kunkel, T., "Rapid and Efficient Site-Specific Mutagenesis Without Phenotypic Selection" Proc. Natl. Acad. Sci. 82: 488-492 (1985).
Lublin et al., "Cloning and Characterization of cDNAs Encoding the Complete Sequence of Decay Accelerating Factor of Human Complement" Molecular Genetics of Complement Workshop (MIT/Endicott House, Boston,MA. Oct. 18-20) (1986).
Medof et al., "Amelioration of Lytic Abnormalities of Paroxysmal Nocturnal Hemoglobinuria with Decay-Accelerating Factor" Proc. Natl. Acad. Sci. 82:2980-2984 (1985).
Nicholson-Weller et al., "Purification From Guinea Pig Erythrocyte Stroma Of A Decay-Acclerating Factor For the Classical C3 Convertase, C4b,2a" J. of Immunology 127:2035-2039 (1981).
Nicholson-Weller et al., "Surface Membrane Expression by Human Blood Leukocytes and Platelets of Decay-Accelerating Factor, a Regulatory Protein of the Complement System" Blood 65(5):1237-1244 (1985).
Nicholson-Weller, A., "Decay Accelerating Factor (CD55)" Current Topics In Microbiology and Immunology 178:14 (1992).
Post et al., "Structure of the Genes for Human Complement Protein Decay Accelerating Factor" J. Immunol. 144(2):740-744 (1990).
Smith, M., "In Vitro Mutagenesis" Ann. Rev. Genet. 19:423-462 (1985).
Wong et al., "Identification of a Partial cDNA Clone for the Human Receptor for Complement Fragments C3b/C4b" Proc. Natl. Acad. Sci. 82:7711-7715 (1985).
Barnstable et al., "Production of Monoclonal Antibodies to Group A Erythrocytes, HLA and Other Human Cell Surface Antigens--New Tools for Genetic Analysis" Cell 14(5):9-20 (May 1978).
Clonis, Y., "Large-scale Affinity Chromatography" Bio/Technology 5:1290-1293 (Dec. 1987).
Cross, G., "Structure of the Variant Glycoproteins and Surface Coat of Trypanosoma brucei" Phil. Trans. R. Soc. London 307:3-12 (1984).
Darnell et al., "Macromolecules in Prokaryotic and Eukaryotic Cells" Molecular & Cellular Biology, Scientific American Books p. 136 (1986).
Davitz et al., "Isolation of Decay Accelerating Factor (DAF) By a Two-step Procedure and Determination of Its N-terminal Sequence" J. Immunol. Meth. 97:71-76 (1987).
Glover, D., "The Principles of Cloning DNA" Gene Cloning: The Mechanics of DNA Manipulation, Second edition, New York:Chapman and Hall pp. 1-20 (1980).
Grantham et al., "Codon Catalog Usage is a Genome Strategy Modulated for Gene Expressivity" Nucleic Acids Research 9(1):r43-r74 (1981).
Kam et al., "Cloning, Sequencing and Chromosomal Localization of Human Term Placental Alkaline Phosphatase cDNA" Proc. Natl. Acad. Sci. USA 82:8715-8719 (Dec. 1985).
Lathe, R., "Synthetic Oligonucleotide Probes Deduced from Amino Acid Sequence Data: Theoretical and Practical Considerations" J. Mol. Biol. 183(1):1-12 (May 5, 1985).
Lublin et al., "Biosynthesis and Glycosylation of Decay-Accelerating Factor" Complement 2:49-50 (1985).
Lublin et al., "Biosynthesis and Glycosylation of the Human Complement Regulatory Protein Decay-accelerating Factor" J. Immunol. 137(5):1629-1635 (Sep. 1, 1986).
Moran et al., "Fusion of Sequence Elements from Non-anchored Proteins to Generate a Fully Functional Signal for Glycophosphatidylinositol Membrane Anchor Attachment" Journal of Cell biology 115(6):1595-1600 (Dec. 1991).
Moran et al., "Human Recombinant Soluble Decay Accelerating Factor Inhibits Complement Activation In Vitro and In Vivo" J. Immunol. 149(5):1736-1743 (Sep. 1, 1992).
Nicholson-Weller et al., "Decay Accelerating Factor (DAF) Peptide Sequences Share Homology with a Consensus Found in the Superfamily of Structurally Related Complement Proteins and Other Proteins Including Haptoglobin, Factor XIII, .beta..sup.2 -glycoprotein I, and the IL-2 Receptor" Immunology Letters 14:307 1986/1987.
Scopes, R., "Immunoadsorbents" Protein Purification: Principles and Practice, Second edition, New York:Springer-Verlag pp. 167-172 (1987).
Seki et al., "A Hydrophobic Tarnsmembrane Segment at the Carboxyl Terminus of Thy-1" Science 227:649-651 (Feb. 8, 1985).
Stryer, L., "Amino Acid Sequence Specifies Three-Dimensional Structure" Biochemistry, Second edition, W.H. Freeman and Company pp. 32-26 (1981).
Sugita et al., "Improved Method for the Isolation and Preliminary Characterization of Human DAF (Decay-Accelerating Factor)" J. Biochem. 100(1):143-150 (1986).
Walters, R., "Affinity Chromatography" Anal. Chem. 57(11):1099A-1114A (Sep. 1985).
D.M. Lublin et al. Ann. Rev. Immunol. 7:35-58, 1989.
R.A. Young et al., Proc. Nat. Acad. Sci. USA 80:1194-1198, Mar. 1983.
W.J. Leonard et al., Nature 311:626, Oct. 1984.
K. Jacobs et al., Nature 313:806, Feb. 28, 1985.
Anderson et al., "Isolation of a Genomic Clone for Bovine Pancreatic Trypsin Inhibitor by Using a Unique-Sequence Synthetic DNA Probe" Proc. Natl. Acad. Sci, USA 80:6838-6842 (1983).
Brodsky et al., "Monclonal Antibodies for Analysis of the HLA System" Immunological Review 47:3-61 (1979).
Caras et al., "Analysis of the Signal Attachment of a Glycophospholipid Membrane Anchor" Journal of Cell Biology 108:1387-1396 (1989).
Caras et al., "Cloning of decay-accelating factor suggests novel use of splicing to generate two proteins" Nature 325:545-549 (Feb. 1987).
Caras et al., "Signal for Attachment of a Phospholipid Membrane Anchor in Decay Accelerating Factor" Science 238:1280-1283 (1987).
Cross, G.A.M., "Eukaryotic protein modification and membrane attachment via phosphatidylinositol" Cell 48:179-181 (1987).
Davitz et al., "Release of decay-accelerating factor (DAF) from the cell membrane by Phophatidylinositol-specific phospholipase" Journal of Experimental Medicine 163:1150-1161 (1985).
Fearon, "Regulation of the amplification C3 convertase of human complement by an inhibitory protein isolated from human erythrocyte membrane" Proc. Natl. Acad. Sci. USA 76(11):5867-5871 (Nov. 1979).
Ferguson et al., "Glcosyl-sn-1,2-dimyristylphosphatidylinositol Is Covalently Linked to Trypanosoma brucei Varioant Surface Glycoprotein" Journal of

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