Decarboxyclavulanic acid thio ethers, their preparation and use

Details Decarboxyclavulanic acid thio ethers, their preparation and use Decarboxyclavulanic acid thio ethers, their preparation and use

1978-08-10

1981-06-23

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2602453, 424246, 424271, 424272, 542413, 542416, C07D49804, A61K 3142

Patent

active

042750679

ABSTRACT:
Compounds of the formula (II): ##STR1## wherein X is S, SO or SO.sub.2 ; and R is (a) an alkyl group of up to 4 carbon atoms, (b) an alkyl group of up to 4 carbon atoms substituted by an OR.sup.1, NHR.sup.1, NH.CO.R.sup.1 or CO.sub.2 R.sup.2 group wherein R.sup.1 is a hydrogen atoms, an alkyl group of up to 4 carbon atoms or benzyl group, and R.sup.2 is a moiety such that CO.sub.2 R.sup.2 is a carboxyl, salted carboxyl or esterified carboxyl group, (c) an aryl group or (d) an aralkyl group are useful for their anti-fungal and .beta.-lactamase inhibitory properties.

REFERENCES:
patent: 4093626 (1978-06-01), Hunt

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