Deazapurine derivatives; a new class of CRF1 specific ligands

Details Deazapurine derivatives; a new class of CRF1 specific ligands Deazapurine derivatives; a new class of CRF1 specific ligands

1995-05-12

1997-07-01

McKane, Joseph

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

540481, 540600, C07D48702

Patent

active

056440570

ABSTRACT:
Disclosed are compounds of the formula ##STR1## wherein Ar represents an aryl or heteroaryl group; and

REFERENCES:
patent: 4605642 (1986-08-01), Rivier et al.
patent: 5063245 (1991-11-01), Abreu et al.
Owens et al., (1991), "Physiology and Pharmacology of Corticotropin-releasing Factor," Pharmacological Reviews, vol. 43, No. 4, pp. 425-473.
Montgomery et al., (1972), "The Use of Enamines in the Synthesis of Heterocycles (1)," J. Het. Chem., vol. 9, pp. 1077-1079.

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