Death domain containing receptor-4 antibodies

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Animal cell – per se – expressing immunoglobulin – antibody – or...

Reexamination Certificate

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C435S326000, C435S334000, C530S350000, C530S387100, C530S387300, C530S388100, C530S388220, C530S389100, C530S391100, C530S391300, C536S023500

Reexamination Certificate

active

06943020

ABSTRACT:
The present invention relates to novel Death Domain Containing Receptor-4 (DR4) proteins which are members of the tumor necrosis factor (TNF) receptor family. In particular, isolated nucleic acid molecules are provided encoding the human DR4 proteins. DR4 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of DR4 activity.

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