Deactivation of antibiotic-hydrolyzing enzymes

Details Deactivation of antibiotic-hydrolyzing enzymes Deactivation of antibiotic-hydrolyzing enzymes

1980-06-27

1982-07-27

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Plural fermentates of different origin

424271, A61K 3500, A61K 3143

Patent

active

043417663

ABSTRACT:
Method and compositions for deactivating bacterial hydrolytic enzymes which attack .beta.-lactam antibiotics.

REFERENCES:
Johnson et al., J. Org. Chem., vol. 28, p. 1927 (1963).
Schragr, Antibiotiki, vol. 17, pp. 461-464 (1972), (Chemical Abstracts 77:56599E).
English et al., Antimicro. Agents Chemother, vol. 14, pp. 414-419 (1978).
Cartwright et al., Nature (London) vol. 278, pp. 360-361 (1979).
Doyle et al. (12/23/61), Nature, p. 1183.
Richards et al. (7/27/63), Nature, p. 354.

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