deA-steroids

Details deA-steroids deA-steroids

1982-10-04

1985-01-08

Milestone, Norma S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424279, C07D30794

Patent

active

044927975

ABSTRACT:
The present disclosure is directed to 5-oxo- or methylene 17.beta.-hydroxy saturated or unsaturated deA-steroids wherein the 17.alpha.-position contains a propionic acid or propanol substituent and derivatives thereof wherein the hydroxy group at the 17-position forms a lactone ring with the carboxy substituent when the substituent at position 21 is carboxy. The deA-steroids and derivatives of the present disclosure are useful as potassium-sparing diuretics or for flushing oedemas.

REFERENCES:
patent: 2971009 (1961-02-01), Burtner
patent: 3766213 (1973-10-01), Furst et al.
patent: 3766256 (1973-10-01), Uskokovic
patent: 3920703 (1975-11-01), Alig et al.
patent: 4119627 (1978-10-01), Wieland
patent: 4140700 (1979-02-01), Furst

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