DCC protein

Details DCC protein DCC protein

1995-05-17

1996-10-01

Patterson, Jr., Charles L.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

A61K 3817, C07K 14435

Patent

active

055612237

ABSTRACT:
A new human gene termed DCC is disclosed. Methods and kits are provided for assessing mutations of the DCC gene in human tissues and body samples. Insertion, deletion, and point mutations in DCC are observed in human tumor cells. Normal tissues express DCC while most colorectal cancers do not. Loss of wild-type DCC genes is associated with neoplastic progression and a diminished life expectancy.

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