Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-08-13
2000-06-27
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514368, 514369, 540451, 540460, C07D51308, C07D51318, C07D51900, A61K 31425, A61K 3170
Patent
active
060807717
ABSTRACT:
DC107 derivatives represented by formula (I) or pharmaceutically acceptable salts thereof which have antimicrobial activity and antitumor activity are provided: ##STR1## wherein R.sup.1 represents CO(CR.sup.4A R.sup.4B).sub.n1 (O(CH.sub.2).sub.p1).sub.n2 OR.sup.5 {wherein n1 represents an integer of 1 or 2; R.sup.4A and R.sup.4B are the same or different, and each represents hydrogen or lower alkyl; p1 and n2 each represents an integer of 1 to 10; and R.sup.5 represents hydrogen, lower alkyl, or the like), or ##STR2##
REFERENCES:
patent: 4999196 (1991-03-01), Nakano et al.
patent: 5733924 (1998-03-01), Kanda et al.
Yamada, et al., Heterocycles, vol. 43, No. 2, (1996) 267-270.
Kanda, et al., Bioorganic & Medicinal Chemistry Letters 8, (1998) 909-912.
Arai Hitoshi
Ashizawa Tadashi
Ikeda Shun-ichi
Kanda Yutaka
Murakata Chikara
Kifle Bruck
Kyowa Hakko Kogyo Co. Ltd.
Shah Mukund J.
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