DC-89 derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514212, 514218, 5142328, 514316, 514322, 514410, 514411, 540602, 544142, 544373, 546187, 546199, 548421, 548433, A61K 31495, A61K 31445, C07D40300, C07D48702

Patent

active

052583830

ABSTRACT:
DC-89 derivatives represented by the formula: ##STR1## wherein X represents hydrogen or CO.sub.2 CH.sub.3 ; and ##STR2## wherein Z represents Cl or Br; R represents hydrogen, CONR.sup.1 R.sup.2 (in which R.sup.1 and R.sup.2 independently represent hydrogen, a straight-chain or branched alkyl group having 1 to 4 carbon atoms or phenyl) or ##STR3## (in which n represents an integer of 0 to 4; R.sup.3 represents CH.sub.2, ##STR4## oxygen, N--CH.sub.3, or N--CH.sub.2 CONR.sup.1 R.sup.2 in which R.sup.1 and R.sup.2 have the same significances as defined above); and W represents hydrogen or ##STR5## (in which W.sup.1 and W.sup.2 independently represent hydrogen or OR.sup.2 in which R.sup.4 represents a straight-chain or branched alkyl group having 1 to 4 carbon atoms or a straight-chain or branched alkenyl group having 2 to 4 carbon atoms, and pharmaceutically acceptable salts thereof have an excellent anti-tumor and antibacterial activity and are expected to be useful as anti-tumor compositions and antibacterial compositions.

REFERENCES:
patent: 4169888 (1979-10-01), Hanaka
patent: 4413132 (1983-11-01), Wierenga
patent: 4423228 (1983-12-01), Wierenga
patent: 4423229 (1983-12-01), Wierenga
patent: 4874756 (1989-10-01), Martens et al.
patent: 4912227 (1990-03-01), Kelley et al.
patent: 4978757 (1990-12-01), Kelly et al.
patent: 4994578 (1991-02-01), Ohba et al.
patent: 5070092 (1991-12-01), Kanda et al.
patent: 5084468 (1992-01-01), Saito et al.
patent: 5117006 (1992-05-01), Saito et al.
patent: 5138059 (1992-08-01), Takahashi et al.
Ichimura et al, CA 115-254225a (1991).
Boger et al, CA 115-84929p (1991), 115-29824a (1991).
Yasuzawa et al CA 115-28949h (1991).
Kanda et al, CA 115-8427h (1991).
Nakano et al, CA 114-41032c (1990).
Ichimura et al, CA 113-207968a (1990).
Bryson et al, CA 110-75859k (1988).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

DC-89 derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with DC-89 derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and DC-89 derivatives will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1757624

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.