DC-89 compounds and process for their preparation

Details DC-89 compounds and process for their preparation DC-89 compounds and process for their preparation

1989-07-17

1992-08-11

Ceperley, Mary E.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548433, C07D48704, C07D47106

Patent

active

051380595

ABSTRACT:
Novel DC-89 compounds represented by the general formula: ##STR1## wherein X represents a single bond or --CH.sub.2 --; and when X represents a single bond, Y represents --CH.sub.2 Br or --CH.sub.2 Cl and when X represents --CH.sub.2 --, Y represents Br, are obtained by the present invention. The compounds have antibacterial and anti-tumor activity.

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patent: 4423228 (1983-12-01), Wierenga
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patent: 4994578 (1991-02-01), Ohba et al.
Warpehoski et al., J. Med. Chem., vol. 31, (1988), pp. 590-603.
Wierenga et al., Adv. Enzyme Regul., Antitumor Analogs of CC-1065, pp. 143-155.
L. Yasuzawa et al., Chem. Pharm. Bull., vol. 36(9), pp. 3728-3731 (1988).

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