DC-52 derivatives and their antitumor use

Details DC-52 derivatives and their antitumor use DC-52 derivatives and their antitumor use

1987-09-29

1989-04-18

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544343, A61K 31495, C07D49822, C07D48718

Patent

active

048228826

ABSTRACT:
Compounds represented by the following formula or by the corresponding hydroquinone type formula: ##STR1## in which R.sup.1 and R.sup.2 are independently hydrogen, lower alkoxy, azido, amino, lower alkylamino, di-lower alkylamino, cyclic amino, lower alkylthio or unsubstituted or substituted arylthio; and X represents hydroxyl and Y represents cyano or X and Y together represents --O-- in the form of --X--Y--, have an excellent antitumor activity.

REFERENCES:
patent: 4650869 (1987-03-01), Hirata
Chem. Abs., vol. 98, No. 11 (1983), 87622z, Kyowa, Ltd.

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