DC-52 derivatives

Details DC-52 derivatives DC-52 derivatives

1990-11-14

1991-12-10

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C07D49822, C07D47118, A61K 31495, C07B 3710

Patent

active

050719840

ABSTRACT:
Disclosed are DC-52 derivatives represented by the formula: ##STR1## wherein each of R.sup.1 and R.sup.2 independently represents hydrogen or hydroxyl, X represents hydroxyl and Y represents cyano and Z represents carboxyl or hydroxymethyl, or pharmacologically acceptable salts thereof. The DC-52 derivatives are useful as antitumor agents.

REFERENCES:
patent: 4650869 (1987-03-01), Hirata
patent: 4822882 (1989-04-01), Sasito
patent: 4946957 (1990-08-01), Saito

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