Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1989-11-13
1991-02-12
Berch, Mark L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
544338, A61K 31495, C07D49822, C07D47118, C07B 3710
Patent
active
049925512
ABSTRACT:
Disclosed are DC-52 derivatives represented by the formula: ##STR1## wherein each of R.sup.1 and R.sup.2 independently represents hydrogen or hydroxyl, X represents hydroxyl and Y represents cyano and Z represents carboxyl or hydroxymethyl, or pharmacologically acceptable salts thereof. The DC-52 derivatives are useful as antitumor agents.
REFERENCES:
patent: 4650869 (1987-03-01), Hirata
patent: 4822882 (1989-04-01), Saito
patent: 4946957 (1990-08-01), Saito
Translation of Claims of JP 57-170189.
Ashizawa Tadashi
Kasai Masaji
Morimoto Makoto
Saito Hiromitsu
Sato Akira
Berch Mark L.
Kyowa Hakko Kogyo Co. Ltd.
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