Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1976-12-02
1978-01-10
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
536 23, 536 24, 536 26, A61K 3170, C07H 1906, C07H 1916
Patent
active
040679683
ABSTRACT:
The antitumor efficacy of the known antibiotics daunomycin (daunorubicin) and adriamycin (doxorubicin) is synergized by the use of said antibiotics together with a daunosamine nucleoside. The latter compounds are prepared by condensing a reactive protected daunosamine with a reactive protected heterocyclic base.
REFERENCES:
patent: 3654262 (1972-04-01), Walton
patent: 3721664 (1973-03-01), Hoffer
patent: 3748320 (1973-07-01), Vorbruggen et al.
patent: 3803124 (1974-04-01), Arcamone et al.
patent: 3817980 (1974-06-01), Vorbruggen et al.
Arcamone Federico
di Marco Aurelio
Lazzari Ettore
Brown Johnnie R.
Societa Farmaceutici Italia S.p.A.
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