Data collection apparatus for use with chemical sensors

Details Data collection apparatus for use with chemical sensors Data collection apparatus for use with chemical sensors

1993-09-29

1996-12-03

Kepplinger, Esther M.

Chemistry: molecular biology and microbiology

Apparatus

Including measuring or testing

4352881, 435 34, 436164, 356349, 2504612, 422 8201, 422 8205, C12M 134, C12Q 104

Patent

active

055807844

ABSTRACT:
An apparatus utilizing chemical sensors to determine whether a particular sample vial is evidencing bacterial growth includes directing radiation sources having closely spaced wavelengths into the sample vial. Emissions from the chemical sensor due to the two spectrally spaced radiation sources are monitored, and a ratio of their differences and sums is calculated. The inventive ratio eliminates station-to-station variation between the radiation sources or detectors, and also any lot-to-lot variations in the sensor materials. An absolute indication of the conditions within the sample vial may thus be taken eliminating the prior art, station-to-station variations and lot-to-lot variations in the sensors resulted in varying readings for positive and negative samples. Thus, any one reading could not be utilized to make a prediction of whether a particular sample is a positive or a negative. With the inventive apparatus, each absolute readings can be utilized to provide an indication of whether a particular sample is positive or negative at any time.

REFERENCES:
patent: 3787124 (1974-01-01), Lowy et al.
patent: 5164301 (1992-11-01), Thompson et al.
patent: 5186536 (1993-02-01), Bornhorst et al.
patent: 5397709 (1995-03-01), Berndt
patent: 5422720 (1995-06-01), Berndt
patent: 5473437 (1995-12-01), Blumenfeld et al.

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