Dairylalkanoids having activity as lipoxygenase inhibitors

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549 75, 549 78, 549 79, 549491, 549495, 549496, 549418, 549501, C07D21106, C07D30748, C07D33322

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active

050774115

ABSTRACT:
The present invention is novel diarylalkanoids having activity as lipoxygenase inhibitors, novel pharmaceutical compositions therefor, and novel methods of use in treating asthma, allergies, cardiovascular diseases, migrains, psoriasis and immunoinflammatory diseases for diarylalkanoids. The compounds of this invention are also useful as cytoprotective agents.

REFERENCES:
patent: 4158063 (1979-06-01), Hitzel et al.
patent: 4562201 (1985-12-01), Stout et al.
patent: 4742083 (1988-05-01), Ritchey et al.
patent: 4810716 (1989-03-01), Connor et al.
patent: 4816487 (1989-03-01), Schewe et al.
CA 92:180781m p. 615 (1980).
E.P.O. Search Report, EPO 87 105 330.2 (1988).

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