D-xylopyranosyl-phenyl-substituted cycles, medicaments...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C536S001110

Reexamination Certificate

active

07417032

ABSTRACT:
D-Glucopyranosyl-phenyl-substituted cycles of general formula Iwherein the groups R1to R6, Z, Cy and R7a, R7b, R7c, R7dare defined as in claim1, have an inhibiting effect on the sodium-dependent glucose cotransporter SGLT. The present invention also relates to pharmaceutical compositions for the treatment of metabolic disorders.

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Accession No. 1987:81540 CAPLUS (Abe et al., “Lignans fromTrachelospermum asiaticum”, Chemical and Pharmaceutical Bulletin, 1986, 34(10), 4340-45).
Adachi et al., “T-1095, a Renal Na+-Glucose Transport Inhibitor”, Metabolism, vol. 49 (8), 2000, 990-995.

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