D-tagatose as anti-hyperglycemic agent

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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514866, A61K 3170

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active

054479177

ABSTRACT:
This invention discloses edible formulations and pharmaceutical compositions containing D-tagatose and the effect of consumption of such formulations on blood level of glucose. D-Tagatose was found to be an anti-hyperglycemic agent. In addition, consumption of D-tagatose in sweetened formulations to inhibit formation of advanced glycosylation end-products in mammals is disclosed. The combination of the anti-hyperglycemic effect and the inhibition of formation of glycosylated proteins and nucleic acids make D-tagatose an ideal agent for alleviating the complications resulting from hyperglycemia, including acceleration of the aging process.

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N. B. Ruderman, A. McCall, pp. 778-797, Medicine, Eds. R. W. Wilkins, N. G. Levinsky, Little Brown Co. Boston 1983.
A. Cerami et al., Glucose and Aging, Scientific American vol. 256, pp. 90-96, 1987.
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H. F. Bunn et al. Reaction of Monosaccharides Science, vol. 213, pp. 222-224, 1981.
G-J. Wolff et al. Chemie Zeitung vol. 103, pp. 232-233 1979.

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