D-Homo-19-norsteroids

Details D-Homo-19-norsteroids D-Homo-19-norsteroids

1977-02-22

1977-11-08

Schwartz, Gerald A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602955P, 2603458R, 2603475, 260586E, 260617A, 260617F, 424266, 424285, 424283, 424308, 424311, 424331, 424343, 560108, 560105, 560139, 560 51, 560124, 560122, C07C 4948, C07C 6902, C07D30922

Patent

active

040575616

ABSTRACT:
D-homosteroids of the formula ##STR1## WHEREIN R.sup.3.alpha. is hydrogen, R.sup.3.beta. is hydroxy, lower alkanoyloxy or aroyloxy and R.sup.3.alpha. and R.sup.3.beta. taken together are oxo; R.sup.17a.alpha. is hydrogen, lower alkyl, ethynyl, vinyl, allyl, methallyl, propadienyl, 1-propynyl, butadiynyl or chloroethynyl; R.sup.17a.beta. is hydrogen, alkanoyl, aroyl, lower alkyl, cycloalkyl-lower-alkyl, benzyl, furfuryl or tetrahydropyranyl; R.sup.18 is hydrogen or methyl and the dotted line in the C-ring denotes an additional carbon to carbon bond in the 11,12-position and
Processes for the preparation thereof are disclosed.
The D-homosteroids of the present invention are useful as ovulation inhibitors and androgenic/anabolic agents.

REFERENCES:
patent: 3984476 (1976-10-01), Furst et al.

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