D-enzyme compositions and methods of their use

Details D-enzyme compositions and methods of their use D-enzyme compositions and methods of their use

2006-10-10

2006-10-10

Witz, Jean C. (Department: 1651)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

C435S018000, C435S023000

Reexamination Certificate

active

07118856

ABSTRACT:
D-enzyme compositions are described comprising an amino acid residue sequence that defines an polypeptide able to catalyze an enzymatic reaction. The D-enzyme has an amino acid residue sequence consisting essentially of D-amino acids.

REFERENCES:
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patent: 5589356 (1996-12-01), Tam
patent: 6040133 (2000-03-01), Kent et al.
Milton et al. “Total Chemical Synthesis of a D-Enzyme: The Enantiomers of HIV-2 Protease Show Demonstrations of Reciprocal Chiral Substrate Specificity” Science (Jun. 5, 1992) 256: 1445-8.

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