D-aminoacylase

Details D-aminoacylase D-aminoacylase

1998-07-24

1999-06-29

Wax, Robert A.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using a micro-organism to make a protein or polypeptide

530350, C12P 2104, C07K 100, C07K 1400, C07K 1700

Patent

active

059167742

ABSTRACT:
This invention provides a novel D-aminoacylase and a method for producing said enzyme, and also a method for producing D-amino acids using said aminoacylase. D-aminoacylase of the invention having novel properties can be derived from a microorganisms belonging to genus Amycolatopsis. The use of the enzyme enables industrial production of D-amino acids.

REFERENCES:
Kameda et al., "Studies on Acylase Activity and Micro-organisms", Chem. Pharm. Bult., 26(9):2698-2704, 1978.
Moriguchi et al., "Production, Purification, and Characterization of D-Aminoacylase from Alicaligenes xylosoxydans subsp. xylosoxydans A-6", Siosc. Biotech. Biochem., 57:1149-1152, 1993.
Sakai et al., "Purification and Properties of D-Aminoacylase from Alcaligenes denitrificans subsp. xylosoxydans MI-4", J. of Fermentation and Bioeng., 71:79-82, 1991.
Sugie et al., "Purification and Properties of D-Aminoalcylase of Streptomyces olivaceus", Agric. Biol. Chem., 42:107-113, 1978.
Sugie et al., "Optical Resolution of DL-Amino Acids with D-Aminoacylase of Streptomyces", Agric. Biol. Chem., 44:1089-1095, 1980.

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