D-amidase and process for producing D-.alpha.-alanine and/or L-.

Details D-amidase and process for producing D-.alpha.-alanine and/or L-. D-amidase and process for producing D-.alpha.-alanine and/or L-.

1992-07-22

1993-10-12

Naff, David M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

435227, 435228, C12P 1306, C12N 978, C12N 980

Patent

active

052524701

ABSTRACT:
A novel D-amidase is described. The enzyme specifically hydrolyzes D-.alpha.-alanineamide into D-.alpha.-alanine. It is produced by culturing a microorganism belonging to the genus Arthrobacter, and is useful as an enzyme for efficiently producing D-.alpha.-alanine having a high optical purity and/or L-.alpha.-alanineamide from DL-.alpha.-alanineamide or D-.alpha.-alanineamide at low cost.

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Journal of Biological Chemistry, "Escherichia coli", vol. 254 (17) pp. 8230-8236.
Goodfellow, M. et al. "Classification in the Biology of the Actinomycetes" 1584; Acad. Press, London, p. 4944.

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