D-.alpha.-(4-hydroxypyridine-3-carbonamido)-p-hydroxyphenylaceta

Details D-.alpha.-(4-hydroxypyridine-3-carbonamido)-p-hydroxyphenylaceta D-.alpha.-(4-hydroxypyridine-3-carbonamido)-p-hydroxyphenylaceta

1974-04-05

1976-03-23

Schwartz, Gerald A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424271, C07D49944

Patent

active

039459950

ABSTRACT:
Penicillins of the formula: ##SPC1##
Wherein R is an unsubstituted phenyl group or a substituted phenyl group having one or more hydroxyl groups or a cyclohexadienyl group and A represents a monocyclic or polycyclic nitrogen-containing heterocyclic aromatic ring, which are useful as antimicrobial agents having a broad antimicrobial spectrum against gram-positive and gram-negative bacteria including Pseudomonas and can be produced advantageously from the phenacyl ester of 6-aminopenicillanic acid through a series of steps.

REFERENCES:
patent: 3248387 (1966-04-01), Alburn et al.
patent: 3433784 (1969-03-01), Long et al.
patent: 3453264 (1969-07-01), Fosker et al.

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