Cytotoxin compound and method of isolation

Details Cytotoxin compound and method of isolation Cytotoxin compound and method of isolation

2005-02-17

2009-12-01

Eyler, Yvonne L. (Department: 1611)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

C514S099000

Reexamination Certificate

active

07625885

ABSTRACT:
A compound or groups of compounds, present in an active principle, derived from tunicates of the speciesSynoicum adareanum, as well as to pharmaceutical compositions comprising these compounds. Extracts from tunicates show selective toxicity against several different cancer cell lines in the NCI 60 cell line panel. These compounds are useful in the effective treatment of cancers, particularly malignant melanomas, colon cancer, and renal cancer cell lines.

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