Cytotoxic T-lymphocyte antigen as cysteine protease inhibitor

Details Cytotoxic T-lymphocyte antigen as cysteine protease inhibitor Cytotoxic T-lymphocyte antigen as cysteine protease inhibitor

1995-06-07

1999-10-05

Elliott, George C.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

530324, 530350, C07K 1400, C07K 14435

Patent

active

059626330

ABSTRACT:
Disclosed are molecules which inhibit the proteolytic activity of cysteine proteases such as Cathespin H, Cathespin L and papain, and methods for using molecules which have the biological properties of cytotoxic T-lymphoyte antigen for inhibiting cysteins proteases and inhibiting proteolglycan degradation.

REFERENCES:
patent: 5189144 (1993-02-01), Asada et al.
patent: 5710014 (1998-01-01), Gottesman et al.
Smith et al "Activity and Deletion Analysis of Recombinant Human Cathespin L Expressed in Escherichia coli" The Journal of Biological Chemistry vol. 264(34):20487-20495, Dec. 5, 1989.

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