Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-06-07
1997-11-04
Owens, Amelia
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549267, A61K 31335
Patent
active
056840365
ABSTRACT:
Novel macrolide compounds, including Lasonolide A and Lasonolide B, have been isolated from a marine sponge. These compounds, analogs, derivatives, or isomers of these compounds, and compositions comprising the compounds or its derivatives, are useful as antitumor agents and as biochemical tools.
REFERENCES:
patent: 3697547 (1972-10-01), Kurath et al.
patent: 4164584 (1979-08-01), Kupchan et al.
patent: 4548814 (1985-10-01), Rinehart, Jr.
patent: 4729996 (1988-03-01), Wright et al.
patent: 4737510 (1988-04-01), Rinehart, Jr.
patent: 4743695 (1988-05-01), Schmitz et al.
patent: 4808590 (1989-02-01), Higa et al.
patent: 4833257 (1989-05-01), Pettit et al.
patent: 4859782 (1989-08-01), Higa et al.
patent: 4873347 (1989-10-01), Hammann et al.
patent: 4996229 (1991-02-01), Moore et al.
patent: 5096922 (1992-03-01), Reichenbach et al.
patent: 5196447 (1993-03-01), Pettit et al.
patent: 5478861 (1995-12-01), Horton et al.
Faulkner, D.J. (1984) "Marine Natural Products: Metabolites of Marine Invertebrates" Natural Products Reports 1:551-598.
Faulkner, D.J. (1966) "Marine Natural Products" Natural Products Reports 3:1-33.
Faulkner, D.J. (1987) "Marine Natural Products" Natural Products Reports 4:539-576.
Uemura, D. et al. (1985) "Norhalichondrin A: An Antitumor Polyether Macrolide from a Marine Sponge" J. Am. Chem. Soc. 107:4796-4798.
Horton, P.A. et al. (1994) "Lasonolide A, A New Cytotoxic Macrolide from the Marine Sponge Forcepia sp." J. Am. Chem. Soc. 116:6015-6016.
Pettit, G.R. et al. (1991) "Synthetic conversion of bryostatin 1 and related bryopyrans" Canadian Journal of Chemistry 69(5):856-860.
Pettit, G.R. et al. (1991) "A Study of the Structure and Dynamics of Dimethyloctadecylsilyl-Modified Silica Using Wide Line .sup.2 H NMR Techniques" Journal of the American Chemical Society 113(17):6693-6695.
Horton Paul A.
Koehn Frank
Longley Ross E.
McConnell Oliver J.
Pomponi Shirley A.
Harbor Branch Oceanographic Institution Inc.
Owens Amelia
LandOfFree
Cytotoxic macrolides and methods of use does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cytotoxic macrolides and methods of use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cytotoxic macrolides and methods of use will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1833390