Cytotoxic factors for modulating cell death

Details Cytotoxic factors for modulating cell death Cytotoxic factors for modulating cell death

2003-11-24

2009-02-17

Helms, Larry R. (Department: 1642)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

C514S002600, C435S004000, C435S007230

Reexamination Certificate

active

07491394

ABSTRACT:
Cytotoxic factors having use in modulating cell death, and their use in methods of treating necrosis or apoptosis-related conditions are disclosed. The invention also relates to methods for identifying active agents useful in treating conditions related to cell death or uncontrolled growth. The present inventors have found that different microorganisms produce different cytotoxic factor(s) having anticancer activity. The substantially pure cytotoxic factors can be used in a method of treating an infectious disease or a cancer.

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