Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1991-02-15
1992-09-01
Nucker, Christine M.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
5303911, 5303915, 530409, 530410, 530807, 435188, C07K 1706, C07K 1714, C07K 1528
Patent
active
051440121
ABSTRACT:
Conjugates of antibodies and cytotoxic methotrexate drugs make use of liners between the drug and antibody which are simple organic groups, wherein the link to the antibody is an acyl group and the link to the drug is an alkylidene hydrazide.
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Johnson David A.
Laguzza Bennett C.
Scott William L.
Eli Lilly and Company
Kim Kay K.
Nucker Christine M.
Parrish John E.
Whitaker Leroy
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