Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1985-03-07
1987-04-28
Foelak, Morton
Drug, bio-affecting and body treating compositions
Lymphokine
424 98, 530387, 530389, 530390, 530395, 530402, 530403, 530404, 530408, A61K 3900, C07K 1706
Patent
active
046613471
ABSTRACT:
A cytotoxic composition is described comprising a moiety having binding affinity to a surface structure of a cell and coupled to a moiety having activity as a structural subunit of C3/C5 convertase.
REFERENCES:
Vogel et al, PNAS, 78(12), pp. 7707-7711, 12/81.
Thorpe et al., Eur. J. Biochem., 116, 447-454 (1981).
Derwent Abstract No. 55398 (European Patent Office Application No. 55115)--Teijin K. K.
Derwent Abstract No. 57670 (European Patent Office Application No. 55575)--Teijin K. K.
Ghose et al., J. Natl. Cancer Inst., 61, 657-676, (1978).
Gilliland et al., Proc. Natl. Acad. Sci., USA 77, 4539-4543 (1980).
Krolick et al., Proc. Natl. Aca. Sci., USA 77, 5419-5423 (1980).
Muller-Eberhard Hans J.
Vogel Carl-Wilhelm E.
Draper Garnette D.
Foelak Morton
Martens William C.
Scripps Clinic
Whitaker Leroy
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