Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1991-01-14
1992-03-10
Russel, Jeffrey E.
Drug, bio-affecting and body treating compositions
Lymphokine
5303919, 530408, 530409, A61K 3944, C07K 1702
Patent
active
050948490
ABSTRACT:
A series of antibody-vinca drug conjugates comprise antibodies which target antigens associated with undesirable cells, so that the cells are controlled or killed by the cytotoxic vinca drug. The drug is linked to the antibody through an organic group comprising a carbonyl at the antibody end, and an alkylidene hydrazide at the vinca end.
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Cullinan George J.
Laguzza Bennett C.
Scott William L.
Eli Lilly and Company
Jones Joseph A.
Kim Kay
Russel Jeffrey E.
Whitaker Leroy
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