Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Patent
1994-11-08
1996-12-24
Guzo, David
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
530350, C07K 1421, C07K 1473
Patent
active
055874550
ABSTRACT:
A chimeric gene directing the synthesis of hybrid recombinant fusion protein in a suitable expression vector has been constructed. The fusion protein possesses the property of selective cytotoxicity against specific virus-infected cells. A CD4(178)-PE40 hybrid fusion protein has been made for selectively killing HIV-infected cells.
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Berger Edward A.
Chaudhary Vijay K.
FitzGerald David
Fuerst Thomas R.
Mizukami Tamio
Guzo David
The United States of America as represented by the Department of
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