Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2008-01-01
2008-01-01
O'Hara, Eileen B. (Department: 1646)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007210, C435S331000, C435S335000, C530S387100, C530S387900, C530S388230
Reexamination Certificate
active
10822787
ABSTRACT:
The invention relates to cytostatin II growth modulatory polypeptides, polynucleotides encoding the polypeptides, methods for producing the polypeptides, in particular by expressing the polynucleotides, and agonists and antagonists of the polypeptides. The invention further relates to methods for utilizing such polynucleotides, polypeptides, agonists and antagonists for applications, which relate, in part, to research, diagnostic and clinical arts.
REFERENCES:
patent: 4444887 (1984-04-01), Hoffmann
patent: 5028534 (1991-07-01), Sadler et al.
patent: 5194596 (1993-03-01), Tischer et al.
patent: 5350836 (1994-09-01), Kopchick et al.
patent: 43 38 817 (1993-11-01), None
patent: 10-286089 (1998-10-01), None
patent: WO94/01548 (1994-01-01), None
patent: WO97/11970 (1997-04-01), None
patent: WO98/45440 (1998-10-01), None
Godbout, Experimental Eye Research, vol. 56, Issue 1, Jan. 1993, pp. 95-106.
Hillier et al., GenBank Accession No. H46792, Jul. 31, 1995.
Yang et al., “Members of the Fatty Acid Binding Protein Family . . . ,” Journal of Cell Biology, 127 (4):1097-1109, Nov. 1994.
Peeters et al., “Cloning of the cDNA encoding human skeletal-muscle,” Biochem Journal, 276:203-207, 1991.
Peeters et al., “Expression inEscherichia coliand characterization of the fatty-acid-binding . . . ,” Biochem Journal, 278:361-364, 1991.
Hillier et al., GenBank Accession No. W76403, Jun. 23, 1996.
De Leon et al., “Fatty Acid Binding Protein Is Induced in Neurons . . . ,” J. of Neuroscience Research, 44:283-292, 1996.
Bohmer et al., “Identification of a Polypeptide Growth Inhibitor . . . ,” Journal of Biological Chemistry, 262 (31):15137-15143, Nov. 5, 1987.
Hillier et al., GenBank Accession No. R60348, May 24, 1995.
Godbout, “Identification and Characterization of Transcripts . . . ,” Exp. Eye Res., 56:95-106, 1993.
Godbout, Genbank Accession No. X65459, Sep. 15, 1993.
Godbout, Genbank Accession No. Q05423, Oct. 1, 1996.
Shimizu et al., “Isolation and expression of a cDNA for human brain fatty acid-binding protein (B-FABP),” Biochimica et Biophysica Acta, 1354:24-28, 1997.
Kim et al., “Tetramerization of an RNA oligonucleotide containing a GGGG sequence,” Letters to Nature, 351:331-332, 1991.
Burton et al., “Heart Fatty Acid Binding Protein Is A Novel Regulator of Cardiac Myocyte Hypertrophy,” Biochemical and Biophysical Research Communications, 205(3):1822-1828, Dec. 30, 1994.
Grosse et al., “5. Mammary-Derived Growth Inhibitor (MDGI),” Dickson et al., Genes, Oncogenes, and Hormones: Advances in Cellular and Molecular Biology of Breast Cancer, Kluwer Academic Publishers, Boston, 1991.
Feng et al., “Brain Lipid-Binding Protein (BLBP) . . . ,” Neuron, 12:895-908, Apr. 1994.
Kleine et al., “Release of heart fatty acid-binding protein into plasma after acute myocardial infarction in man,” Molecular and Cellular Biochemistry, 116:155-162, 1992.
Kurtz et al., “The expression pattern of a novel gene encoding brain-fatty acid binding . . . ,” Development, 120:2637-2649, 1994.
Kurtz et al., “Developmental Regulation of Mammary-derived Growth Inhibitor . . . ,” Journal of Cell Biology, 110:1779-1789, May 1990.
Treuner et al., “Cloning and characterization of the mouse gene encoding . . . ,” Gene, 147:237-242, 1994.
Ngo et al., “Computational Complexity, Protein Structure Prediction, and the Levinthal Paradox,” The Protein Folding Problem and Tertiary Structure Prediction, Mertz et al., Birkhauser Boston, 433-395, 1994.
Huynh et al., “Tumor Suppressor Activity of the Gene Encoding Mammary-derived Growth Inhibitor,” Cancer Research, 55:2225-2231, Jun. 1, 1995.
Hillier et al., GenBank Accession No. N57521, Feb. 22, 1996.
Hillier et al., GenBank Accession No. N47671, Feb. 14, 1996.
Siegenthaler et al., “Purification and characterization of the human epidermal fatty acid-binding protein . . . ,” Biochem. J., 302:363-371.
Veerkamp et al., “Structural and functional features of different types of cytoplasmic fatty acid-binding proteins,” Biochimica et Biophysica Acta., 1081:1-24, Jan. 4, 1991.
Veerkamp and Maatman, “Cytoplasmic Fatty Acid-Binding Proteins: Their Structure and Genes,” Pro. Lipid Res., 34(1):17-52, 1995.
Hillier et al., The WashU-Merck EST Project, Accession No. H46792.
Benjamin et al., “A plasticity window for blood vessel remodelling is defined by pericyte coverage . . . ,” Development, 125:1591-1598, 1998.
Vukicevic et al., “Induction of nephrogenic mesenchyme by osteogenic protein 1 . . . ,” Proc. Natl. Acad. Sci. USA, 93:9021-9026, 1996.
Massague, J., “The TGF-beta Family of Growth and Differentiation Factors,” Cell. 49:437-438, May 22, 1987.
Pilbeam et al., “Comparison of the Effects of Various Lengths of Synthetic Human Parathyroid . . . ,” Bone, 14:717-720, 1993.
Bowie et al., “Deciphering the Message in Protein Sequences . . . ,” Science, 247:1306-1310, Mar. 16, 1990.
Vukicevic et al., “Induction of nephrogenic mesenchyme by osteogenic protein 1 (bone morphogenetic protein 7)” PNAS USA 93:9021-9026 (Aug. 1996).
Shi et al., Database SwissProt—40, Accession No. 015540 (Dec. 1996).
Gentz Reiner L.
Ni Jian
Yu Guo-Liang
Human Genome Sciences Inc.
Human Genome Sciences Inc.
O'Hara Eileen B.
LandOfFree
Cytostatin II antibodies and methods does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cytostatin II antibodies and methods, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cytostatin II antibodies and methods will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3909255