Cytosine derivatives having histamine H.sub.2 -antagonist activi

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514212, 514274, 2602433, 544284, 544286, 544317, A61K 31505, C07D40112

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active

045713987

ABSTRACT:
This invention relates to cytosine derivatives which have histamine H.sub.2 -antagonist activity. A specific compound of this invention is 4-[3-(3-(piperidinomethyl)phenoxy)propylamino]-pyrimidin-2-thione.

REFERENCES:
patent: 3932644 (1976-01-01), Durant et al.
patent: 4234588 (1980-11-01), Brown et al.
patent: 4374836 (1983-02-01), Yellin et al.
patent: 4385058 (1983-05-01), Cooper et al.
patent: 4463005 (1984-07-01), Jones et al.
Derwent Abstract 38240c (EP 13,071) Jul. 9, 1980.

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