Cytoreceptor assay

Chemistry: molecular biology and microbiology – Maintaining blood or sperm in a physiologically active state...

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435 7, 436504, G01N 3356, G01N 3358

Patent

active

043754597

ABSTRACT:
Novel assays are provided employing specific ells having cytoreceptors for an analyte. The assay combines the specific cells, the sample, and a tagged analyte, normally radioactively tagged. After a sufficient time, the cells are separated, conveniently by centrifugation, and either the supernatant or the cells assayed for the signal resulting from the tag.

REFERENCES:
patent: 4092116 (1978-05-01), Giaever
patent: 4247536 (1981-01-01), Fruitstong et al.
patent: 4282315 (1981-08-01), Luderer et al.
Parker, Radio Immunoassay of Biologically Active Compounds, Prentice-Hall, Inc., N.J., 1976, pp. 180-189.
Cullen et al., The Journal of Immunology, vol. 117, No. 1, Jul. 1976, pp. 136-142.
Bizollon ed., Radioimmunology 1979, Elsevier/North Holland Biomedical Press, Amsterdam, 1979, pp. 161-170.

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