Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1976-02-17
1978-03-28
Rosen, Sam
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
424317, A61K 31215, A61K 3119
Patent
active
040815536
ABSTRACT:
The present invention provides a method for treatment of Crohn's disease, inflammatory bowel disease, infectious enteritis, sprue, and intestinal inflammatory disease secondary to radiation exposure or an intestinally-manifested allergic response to foodstuffs which comprises administrating a cytoprotective prostaglandin to a human who suffers from one of said diseases. Cytoprotective prostaglandins refer to those prostaglandin-type compounds which are useful in reducing the incidence of NOSAC-induced lesions in the intestinal wall of the rat. "NOSAC" is an abbreviation for "non-steroidal antiinflammatory compound."
REFERENCES:
patent: 3849487 (1974-11-01), Bundy
patent: 3927213 (1975-12-01), Lippmann
patent: 3928588 (1975-12-01), Robert
Armitage Robert A.
Rosen Sam
The Upjohn Company
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