Cytoprotective fatty moiety compounds

Details Cytoprotective fatty moiety compounds Cytoprotective fatty moiety compounds

1995-06-07

1997-08-19

Carr, Deborah D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Fatty compounds having an acid moiety which contains the...

554 94, 554103, 554108, 554110, 554223, 554224, 554227, C07B 4500

Patent

active

056590555

ABSTRACT:
Water or lipid soluble, pharmacologically active, antioxidant, anti-phospholipase compounds that are chemically defined. The compounds protect mammalian cells by inhibiting PLA.sub.2 and preventing oxidation. In particular, each compound has at least two fatty moieties and no active hydroxy group. The compound may also have at least one ionizable group, which may be a carboxyl group, and each of the fatty moieties has from sixteen to twenty carbon atoms and at least one cis-unsaturated double bond.

REFERENCES:
patent: 4701469 (1987-10-01), Mendy et al.
Chemical Abstracts, 103:183451, O'Brien et al., abstract of article including compound, "Preparation and characterization od polymerized liposomes". 1985.

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