Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1987-10-30
1991-08-13
Moskowitz, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
530387, 435 7021, 43524027, 935104, C07K 1506, C07K 1528, C12P 2108, C12N 520
Patent
active
050397931
ABSTRACT:
A protein characterized by the fact that it is a nonkeratinic protein present in the cytoplasm of suprabasal epidermal cells, in particular in man, and absent in basocellular carcinoma, melanoma and naevus cells; antibodies directed against said protein, their preparation and their application as reagents; cellular stocks secreting such antibodies, and their preparation.
REFERENCES:
Stedman's Medical Dictionary 24th Edition, 1982 Williams & Wilkins.
Proc. Natl. Acad. Sci. USA, vol. 83; No. 8, Apr. 1986, pp. 2657-2661, Parrish et al.: "Mouse antisera specific for desmosomal adhesion molecules of suprabasal skin cells, meninges, meningioma".
Chemical Abstracts, vol. 100; No. 21, May 1984; page 453, No. 172635k, Weiss et al.
Biological Abstracts, vol. 78; No. 8, Aug. 1984, No. 60667, Murphy et al.: "Involucrin expression in normal and neoplastic human skin: A marker for kerationocyte differentiation".
Cancer Research, vol. er, Feb. 1985; pp. 783-790, Hamburger et al: "Isolation and characterization of a monoclonal antibody specific for epithelial cells".
Biological Abstracts, vol. 80, No. 1, Jul. 1985, No. 4165, Viac et al.: "A monoclonal antibody labeling the keratinocyte membrane: A marker of epidermal differentiation".
Proc. Natl. Acad. Sci. U.S.A., vol. 83; No. 19, Oct. 1986, pp. 7282-7286, Jones et al.: "A cell surface desmosome-associated component: Identification of a tissue-specific cell adhesion molecule".
Chemical Abstracts, vol. 105, No. 11; Sep. 1986, page 480, No. 95671t, Bernard.
Chemical Abstracts, vol. 105; No. 7, Aug. 1986, page 411, No. 58395k, King et al.
Chemical Abstracts, vol. 105; No. 7, Aug. 1986, page 438, No. 58657x, Ma et al.
Bernard Bruno
Darmon Yves M.
Centre International de Recherches Dermatologiques
Moskowitz Margaret
Sidberry Hazel F.
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