Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Reexamination Certificate
2006-10-05
2009-02-03
Saoud, Christine J (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
C530S350000, C530S412000, C530S413000, C435S069520, C435S069700
Reexamination Certificate
active
07485699
ABSTRACT:
The present invention relates to polynucleotide and polypeptide molecules for zcyto20, zcyto21, zcyto22, zycto24, and zcyto25 proteins which are most closely related to interferon-α at the amino acid sequence level. The receptor for this protein family is a class II cytokine receptor. The present invention includes methods of reducing viral infections and increasing monocyte counts. The present invention also includes antibodies to the zcyto20 polypeptides, and methods of producing the polynucleotides and polypeptides.
REFERENCES:
patent: 6927040 (2005-08-01), Sheppard et al.
patent: 0 032 134 (1981-07-01), None
patent: 00/55324 (2000-09-01), None
patent: WO02/20569 (2002-03-01), None
patent: WO02/092762 (2002-11-01), None
patent: 03/066002 (2003-08-01), None
University Calif. Santa Cruz Genome Browser Database—Aug. 6, 2001, Accession No. C19001210.
University Calif. Santa Cruz Genome Browser Database—Aug. 6, 2001, Accession No. C19001212.
University Calif. Santa Cruz Genome Browser Database—Aug. 6, 2001, Accession No. C19001213.
University Calif. Santa Cruz Genome Browser Database—Dec. 22, 2001, Accession No. C19001260.
University Calif. Santa Cruz Genome Browser Database—Dec. 22, 2001, Accession No. C19001256.
University Calif. Santa Cruz Genome Browser Database—Dec. 22, 2001, Accession No. C19001257.
Ensembl Contig. View Sanger Institute—Apr. 19, 2001, Accession No. AC011445.
Ensembl Contig. View Sanger Institute—Apr. 18, 2000, Accession No. AC018477.
University Calif. Santa Cruz Genome Browser—Chromosome 19, Apr. 20, 2001.
Adams et al., “3,400 expressed sequence tags identify diversity of transcripts from human brian,”Nat. Genet. 4:256-267 (1993).
GenBank Submission XP-002202436, Oct. 12, 2000.
GenBank Submission XP-002202437, Dec. 12, 1999.
Sheppard et al., “IL-28, IL-29 and their class II cytokine receptor IL-28R,”Nature Immun. 4(1):63-68, 2002.
Kotenko et al., “IFN-λs mediate antiviral protection through a distinct class II cytokine receptor complex,”Nature Immun. 4(1):69-77, 2002.
Kindsvogel et al., “Novel Interferon-Like Cytokines not Recognized by the Type I Interferon Receptor,”J. Interferon Cytokine Res. 22(1):S-48, 2002.
Brack et al., “Molecular Analysis of the Human Interferon-Alpha Gene Family,”Gene 15:379-394, 1981.
Xie et al., “Interleukin (IL)-22, a Novel Human Cytokine That Signals through the Interferon Receptor-related Proteins CRF2-4 and IL-22R,”J. Biol. Chem. 275(40):31335-31339, 2000.
Database Embl Sequence Library EBI. Hinxton—Oct. 8, 1999, Accession No. AC011445.
Vilcek, “Novel interferons,”Nature Immunology 4(I):8-9, 2003.
Burge et al., “Prediction of Complete Gene Structures in Human Genomic DNA,”J. Mol. Biol. 268:78-94, 1997.
Fox Brian A.
Kindsvogel Wayne
Klucher Kevin M.
Sheppard Paul O.
Taft David W.
Saoud Christine J
Seharaseyon Jegatheesan
Walsh Brian J.
ZymoGenetics Inc.
LandOfFree
Cytokine protein family does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cytokine protein family, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cytokine protein family will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4086089