Cytokine inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C548S255000

Reexamination Certificate

active

10718380

ABSTRACT:
Disclosed are compounds of formula (I)Where Ar1, X, R3, R4, R5and R6are defined herein. The compounds of the invention inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.

REFERENCES:
patent: 6319921 (2001-11-01), Cirillo et al.
patent: 2001/0044445 (2001-11-01), Bamaung et al.
patent: 2005/0153972 (2005-07-01), Cogan et al.
patent: 2005/0256113 (2005-11-01), Cogan et al.
patent: 4302051 (1994-07-01), None
patent: WO 96/32382 (1996-10-01), None
patent: WO 00/18738 (2000-04-01), None
patent: WO 00/24735 (2000-05-01), None
patent: WO 03/022820 (2003-03-01), None
patent: WO 03/029210 (2003-04-01), None
patent: WO 03/030902 (2003-04-01), None
patent: WO 03/063781 (2003-08-01), None
Tsuboi et al., 2002, CAS: 137:263038.
DE 4302051: Abstract for Correspondent EP 0608858.

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